Just as a fine bottle of wine benefits from being given time to breathe, the Wimbledon vintage is just that little more special after a day off. There are no real weak spots on his armour, as you can expect from the world number 1, save for his weak second delivery.
Centre Court and Court One have so far hosted 25 men's matches and 17 women's matches. That was the one Murray gave up to a buccaneering Fabio Fognini last time out and while that troublesome hip of Andrew's makes a nation uneasy, it's still hard to envision anyone from outside that quartet breaking their 14-year stranglehold on ownership of the Challenge Cup.
"I've done a good job so far here", said Murray, the defending champion. "I'm still pumped to get out there regardless of whether there are other British players playing the tournament or not". I'm really pleased with that. I do think that's the case. But previous year Querrey claimed the scalp of defending champion Novak Djokovic and Murray will be aware that this is a big step up.
The 24th-seeded Querrey pumped 31 aces and only one double fault edging Kevin Anderson, 5-7, 7-6 (5), 6-3, 6-7 (11), 6-3, in three hours, six minutes.
Johanna Konta joined Murray in the quarterfinal after beating Caroline Garcia in three sets.
Simona Halep of Romania could unseat Kerber at the top of the rankings but she has the imposing presence of Victoria Azarenka, quickly back in form after her maternity leave, standing between her and a place in the quarter-finals.
Murray became just the third player in the Open era after Jimmy Connors and Roger Federer to reach 10 consecutive quarter-finals at a single grand slam.
"It's a great opportunity, every single time you step on the court, to grow, to learn something more about yourself". I'm not here waiting for anybody to play badly or not be who they once were. He has a great serve, a great volley.
You would not find Paire's idiosyncratic forehand in any coaching manuals, but the Frenchman's two-handed backhand is a major weapon.
A four-set win got Wimbledon underway for Paire against Rogerio Dutra Da Silva, before he came away with a straight-sets victory over the more fancied Pierre-Hugues Herbert.
You have to go back 44 years to the last time the home nation had a man and woman in the quarter-finals, with Roger Taylor and Virginia Wade both making the last eight. Murray attacked behind a bold serve thumping a smash to save the second break point. In the victory, Querrey won 83 percent of his first serve points and 59 percent of his second serve points.
Once dominance had been established, Murray looked more content with his game, but there was plenty of work to do after swapping breaks with a still ambitious opponent.
When Paire went 0-40 down at 2-2 in the third set it seemed that the end might be swift, but the Frenchman dug deep to hold on to his serve and had a break point for a 5-3 lead when Murray served at 3-4.
The match-up against Paire will be Murray's 110th match against French opposition in his career and he has come out on the winning side a remarkable 94 times. She finally won by converting her eighth match point.
The Scot said: "I've met them quite a few times, been to some of their fights".
"I think he has no problem", said the world number 46.
He won the pair's only encounter on the clay of Monte Carlo past year however Paire gave him a scare by winning the first set 6-2.